{ "openapi": "3.0.1", "info": { "title": "Clinical Trial Protocol Amendments — ClinicalTrials.gov Diff", "description": "Track what actually changed between ClinicalTrials.gov record versions: primary endpoints re-specified, enrollment cut, eligibility widened, completion dates slipped, trials terminated. Structured before/after diffs with day shifts, percent changes and a critical/major/minor rating.", "version": "0.0", "x-build-id": "na29set4yqqqGhyFL" }, "servers": [ { "url": "https://api.apify.com/v2" } ], "paths": { "/acts/malekh~clinical-trial-protocol-amendments/run-sync-get-dataset-items": { "post": { "operationId": "run-sync-get-dataset-items-malekh-clinical-trial-protocol-amendments", "x-openai-isConsequential": false, "summary": "Executes an Actor, waits for its completion, and returns Actor's dataset items in response.", "tags": [ "Run Actor" ], "requestBody": { "required": true, "content": { "application/json": { "schema": { "$ref": "#/components/schemas/inputSchema" } } } }, "parameters": [ { "name": "token", "in": "query", "required": true, "schema": { "type": "string" }, "description": "Enter your Apify token here" } ], "responses": { "200": { "description": "OK" } } } }, "/acts/malekh~clinical-trial-protocol-amendments/runs": { "post": { "operationId": "runs-sync-malekh-clinical-trial-protocol-amendments", "x-openai-isConsequential": false, "summary": "Executes an Actor and returns information about the initiated run in response.", "tags": [ "Run Actor" ], "requestBody": { "required": true, "content": { "application/json": { "schema": { "$ref": "#/components/schemas/inputSchema" } } } }, "parameters": [ { "name": "token", "in": "query", "required": true, "schema": { "type": "string" }, "description": "Enter your Apify token here" } ], "responses": { "200": { "description": "OK", "content": { "application/json": { "schema": { "$ref": "#/components/schemas/runsResponseSchema" } } } } } } }, "/acts/malekh~clinical-trial-protocol-amendments/run-sync": { "post": { "operationId": "run-sync-malekh-clinical-trial-protocol-amendments", "x-openai-isConsequential": false, "summary": "Executes an Actor, waits for completion, and returns the OUTPUT from Key-value store in response.", "tags": [ "Run Actor" ], "requestBody": { "required": true, "content": { "application/json": { "schema": { "$ref": "#/components/schemas/inputSchema" } } } }, "parameters": [ { "name": "token", "in": "query", "required": true, "schema": { "type": "string" }, "description": "Enter your Apify token here" } ], "responses": { "200": { "description": "OK" } } } } }, "components": { "schemas": { "inputSchema": { "type": "object", "properties": { "nctIds": { "title": "Studies to scan", "type": "array", "description": "The trials to diff, by NCT identifier. Case does not matter — \"nct01439386\" normalises. To carry your own identifier into the output, pass objects instead of strings: {\"recordId\": \"COMP-1\", \"nctId\": \"NCT02576574\"}; recordId is echoed on every row, including errors. Leave empty and use the search fields below to build the list instead — you can also combine the two, and duplicates are removed." }, "since": { "title": "Only amendments on or after", "type": "string", "description": "Ignore protocol changes older than this date (YYYY-MM-DD; a bare year or year-month is accepted). This is the main cost control on an actively-amended trial — a study registered in 2010 can carry 60 versions. Leave empty to diff the study's entire version history." }, "minSignificance": { "title": "Minimum significance", "enum": [ "minor", "major", "critical" ], "type": "string", "description": "How large a change has to be before it is reported. \"critical\" is reserved for changes that undermine comparability — primary outcome measures re-specified, the trial terminated or withdrawn. \"major\" adds enrollment and eligibility changes and completion-date slips. \"minor\" adds everything else, including contact and administrative edits.", "default": "major" }, "includeMinorChanges": { "title": "Include minor changes", "type": "boolean", "description": "Shortcut that forces the minimum significance down to \"minor\", overriding the setting above. Useful when you want the full audit trail rather than a competitive-intelligence view.", "default": false }, "searchCondition": { "title": "Search: condition", "type": "string", "description": "Build the study list by condition or disease, e.g. \"non-small cell lung cancer\". Combines with the sponsor, term and status filters; the matched NCT ids are added to anything given above, up to the maximum-studies cap." }, "searchSponsor": { "title": "Search: sponsor", "type": "string", "description": "Build the study list by lead sponsor or collaborator, e.g. \"Pfizer\". This is the usual way to watch a competitor's whole trial portfolio for protocol changes." }, "searchQuery": { "title": "Search: free-text term", "type": "string", "description": "Free-text search across the study record, passed through to the ClinicalTrials.gov v2 API as query.term. Use for anything the condition and sponsor fields do not cover — an intervention name, a device, a mechanism." }, "searchStatus": { "title": "Search: overall status", "type": "array", "description": "Restrict the search to these recruitment statuses, e.g. RECRUITING, ACTIVE_NOT_RECRUITING, TERMINATED. Applies only to studies found by search, not to NCT ids you supplied directly.", "items": { "type": "string" } }, "maxStudies": { "title": "Maximum studies", "minimum": 1, "maximum": 500, "type": "integer", "description": "Safety cap on how many studies are scanned, counting both the ids you supplied and anything the search adds, so a broad sponsor search cannot run up an unexpected bill. You are charged per study scanned.", "default": 25 }, "maxAmendmentsPerStudy": { "title": "Maximum amendments per study", "minimum": 1, "maximum": 200, "type": "integer", "description": "Caps how many amendments are reported for any one study, so a single heavily-revised trial cannot dominate the results. Amendments are reported newest first, so the cap drops the oldest.", "default": 20 }, "maxVersionFetches": { "title": "Version-fetch budget", "minimum": 1, "maximum": 4000, "type": "integer", "description": "Hard ceiling on total historical-version fetches across the whole run — the real compute cost here, since each amendment needs the record on both sides of it. Raise it if you are scanning many long-running trials and see the budget reported as exhausted; the default comfortably covers 25 studies.", "default": 600 } } }, "runsResponseSchema": { "type": "object", "properties": { "data": { "type": "object", "properties": { "id": { "type": "string" }, "actId": { "type": "string" }, "userId": { "type": "string" }, "startedAt": { "type": "string", "format": "date-time", "example": "2025-01-08T00:00:00.000Z" }, "finishedAt": { "type": "string", "format": "date-time", "example": "2025-01-08T00:00:00.000Z" }, "status": { "type": "string", "example": "READY" }, "meta": { "type": "object", "properties": { "origin": { "type": "string", "example": "API" }, "userAgent": { "type": "string" } } }, "stats": { "type": "object", "properties": { "inputBodyLen": { "type": "integer", "example": 2000 }, "rebootCount": { "type": "integer", "example": 0 }, "restartCount": { "type": "integer", "example": 0 }, "resurrectCount": { "type": "integer", "example": 0 }, "computeUnits": { "type": "integer", "example": 0 } } }, "options": { "type": "object", "properties": { "build": { "type": "string", "example": "latest" }, "timeoutSecs": { "type": "integer", "example": 300 }, "memoryMbytes": { "type": "integer", "example": 1024 }, "diskMbytes": { "type": "integer", "example": 2048 } } }, "buildId": { "type": "string" }, "defaultKeyValueStoreId": { "type": "string" }, "defaultDatasetId": { "type": "string" }, "defaultRequestQueueId": { "type": "string" }, "buildNumber": { "type": "string", "example": "1.0.0" }, "containerUrl": { "type": "string" }, "usage": { "type": "object", "properties": { "ACTOR_COMPUTE_UNITS": { "type": "integer", "example": 0 }, "DATASET_READS": { "type": "integer", "example": 0 }, "DATASET_WRITES": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_READS": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_WRITES": { "type": "integer", "example": 1 }, "KEY_VALUE_STORE_LISTS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_READS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_WRITES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_INTERNAL_GBYTES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_EXTERNAL_GBYTES": { "type": "integer", "example": 0 }, "PROXY_RESIDENTIAL_TRANSFER_GBYTES": { "type": "integer", "example": 0 }, "PROXY_SERPS": { "type": "integer", "example": 0 } } }, "usageTotalUsd": { "type": "number", "example": 0.00005 }, "usageUsd": { "type": "object", "properties": { "ACTOR_COMPUTE_UNITS": { "type": "integer", "example": 0 }, "DATASET_READS": { "type": "integer", "example": 0 }, "DATASET_WRITES": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_READS": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_WRITES": { "type": "number", "example": 0.00005 }, "KEY_VALUE_STORE_LISTS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_READS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_WRITES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_INTERNAL_GBYTES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_EXTERNAL_GBYTES": { "type": "integer", "example": 0 }, "PROXY_RESIDENTIAL_TRANSFER_GBYTES": { "type": "integer", "example": 0 }, "PROXY_SERPS": { "type": "integer", "example": 0 } } } } } } } } } }