{ "openapi": "3.0.1", "info": { "title": "ClinicalTrials.gov Search — Trials, Sponsors and Sites", "description": "Search the US registry of clinical studies by condition, drug, sponsor, phase, status and country, and get back flat rows: title, sponsor, phase, enrollment, eligibility, primary outcome and the recruiting sites. 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Several lines widen the search: a trial matching any one of them is returned. The registry expands synonyms, so 'heart attack' also finds trials indexed under myocardial infarction.", "default": [ "type 2 diabetes" ], "items": { "type": "string" } }, "interventions": { "title": "Drugs or interventions", "type": "array", "description": "Drug names, devices, procedures or behavioural interventions, one per line — for example pembrolizumab, semaglutide. Brand and generic names both work; the registry indexes the other names a sponsor declared.", "items": { "type": "string" } }, "sponsor": { "title": "Sponsor or collaborator", "type": "string", "description": "Organisation running or funding the trial — Pfizer, Mayo Clinic, National Cancer Institute. This matches collaborators as well as the lead sponsor, so a Pfizer search also returns academic trials Pfizer co-funded. The returned row carries both, so you can tell which is which. Matching is on whole words, not on prefixes: 'Moderna' finds 1 trial, 'ModernaTX' finds 142, because the registry spells the company ModernaTX, Inc. Extra words narrow rather than widen — 'Pfizer' returns 6 085 trials and 'Pfizer Inc' returns 705. Check the leadSponsor column of a small run before scaling up." }, "query": { "title": "Free text", "type": "string", "description": "Searches the whole record — title, summary, eligibility, outcomes, keywords. Use it for anything the fields above do not cover, such as a biomarker (EGFR exon 20) or a trial design term (crossover)." }, "statuses": { "title": "Recruitment status", "type": "array", "description": "Keep only trials in these states. Leave empty for all. TERMINATED and WITHDRAWN are the interesting ones for competitive work — they are the programmes that stopped, and the record says when. UNKNOWN means the sponsor has not updated the record past its expected completion date.", "items": { "type": "string", "enum": [ "RECRUITING", "NOT_YET_RECRUITING", "ENROLLING_BY_INVITATION", "ACTIVE_NOT_RECRUITING", "COMPLETED", "SUSPENDED", "TERMINATED", "WITHDRAWN", "UNKNOWN", "AVAILABLE", "NO_LONGER_AVAILABLE", "TEMPORARILY_NOT_AVAILABLE", "APPROVED_FOR_MARKETING", "WITHHELD" ] }, "default": [] }, "recruitingOnly": { "title": "Currently recruiting only", "type": "boolean", "description": "Shorthand for the two statuses a patient or a site-feasibility team cares about: RECRUITING and NOT_YET_RECRUITING. Overrides the status list above.", "default": false }, "phases": { "title": "Phases", "type": "array", "description": "Keep only these phases. Leave empty for all. A trial can declare two phases at once (PHASE1 and PHASE2), and asking for PHASE2 returns it. NA is the value used by trials with no phase — device, behavioural and most observational work.", "items": { "type": "string", "enum": [ "EARLY_PHASE1", "PHASE1", "PHASE2", "PHASE3", "PHASE4", "NA" ] }, "default": [] }, "studyType": { "title": "Study type", "enum": [ "any", "INTERVENTIONAL", "OBSERVATIONAL", "EXPANDED_ACCESS" ], "type": "string", "description": "Interventional trials test something on assigned arms. Observational studies watch a cohort. Expanded access is compassionate-use supply, not a trial.", "default": "any" }, "locationCountry": { "title": "Country", "type": "string", "description": "Keep only trials with at least one site in this country. Use the registry's own spelling — United States, United Kingdom, Czechia, Turkey (Türkiye), South Korea." }, "locationTerm": { "title": "City, state or region", "type": "string", "description": "A finer location search than the country filter — Boston, Bavaria, Île-de-France. This is a text match on the site addresses, not a radius, so it will not find a hospital in a neighbouring town." }, "sortBy": { "title": "Sort by", "enum": [ "relevance", "LastUpdatePostDate:desc", "StudyFirstPostDate:desc", "StartDate:desc", "EnrollmentCount:desc" ], "type": "string", "description": "Relevance is best for a narrow question. 'First posted' is how you watch a field for new entrants. 'Enrollment' surfaces the large registrational trials.", "default": "relevance" }, "maxResults": { "title": "Maximum trials", "minimum": 1, "maximum": 8000, "type": "integer", "description": "Cap on trials returned. The registry holds well over half a million studies, so a broad search without a cap is a very long run.", "default": 100 }, "locationsPerTrial": { "title": "Sites listed per trial", "minimum": 0, "maximum": 100, "type": "integer", "description": "A phase 3 trial can list several hundred sites. The row always carries the full locationCount and the list of countries; this controls how many individual sites are spelled out. Set to 0 for counts only.", "default": 5 }, "includeEligibility": { "title": "Include full eligibility criteria", "type": "boolean", "description": "The sponsor's full inclusion and exclusion text. It is long — often several thousand characters — but it is the field that decides whether a patient fits.", "default": true } } }, "runsResponseSchema": { "type": "object", "properties": { "data": { "type": "object", "properties": { "id": { "type": "string" }, "actId": { "type": "string" }, "userId": { "type": "string" }, "startedAt": { "type": "string", "format": "date-time", "example": "2025-01-08T00:00:00.000Z" }, "finishedAt": { "type": "string", "format": "date-time", "example": "2025-01-08T00:00:00.000Z" }, "status": { "type": "string", "example": "READY" }, "meta": { "type": "object", "properties": { "origin": { "type": "string", "example": "API" }, "userAgent": { "type": "string" } } }, "stats": { "type": "object", "properties": { "inputBodyLen": { "type": "integer", "example": 2000 }, "rebootCount": { "type": "integer", "example": 0 }, "restartCount": { "type": "integer", "example": 0 }, "resurrectCount": { "type": "integer", "example": 0 }, "computeUnits": { "type": "integer", "example": 0 } } }, "options": { "type": "object", "properties": { "build": { "type": "string", "example": "latest" }, "timeoutSecs": { "type": "integer", "example": 300 }, "memoryMbytes": { "type": "integer", "example": 1024 }, "diskMbytes": { "type": "integer", "example": 2048 } } }, "buildId": { "type": "string" }, "defaultKeyValueStoreId": { "type": "string" }, "defaultDatasetId": { "type": "string" }, "defaultRequestQueueId": { "type": "string" }, "buildNumber": { "type": "string", "example": "1.0.0" }, "containerUrl": { "type": "string" }, "usage": { "type": "object", "properties": { "ACTOR_COMPUTE_UNITS": { "type": "integer", "example": 0 }, "DATASET_READS": { "type": "integer", "example": 0 }, "DATASET_WRITES": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_READS": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_WRITES": { "type": "integer", "example": 1 }, "KEY_VALUE_STORE_LISTS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_READS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_WRITES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_INTERNAL_GBYTES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_EXTERNAL_GBYTES": { "type": "integer", "example": 0 }, "PROXY_RESIDENTIAL_TRANSFER_GBYTES": { "type": "integer", "example": 0 }, "PROXY_SERPS": { "type": "integer", "example": 0 } } }, "usageTotalUsd": { "type": "number", "example": 0.00005 }, "usageUsd": { "type": "object", "properties": { "ACTOR_COMPUTE_UNITS": { "type": "integer", "example": 0 }, "DATASET_READS": { "type": "integer", "example": 0 }, "DATASET_WRITES": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_READS": { "type": "integer", "example": 0 }, "KEY_VALUE_STORE_WRITES": { "type": "number", "example": 0.00005 }, "KEY_VALUE_STORE_LISTS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_READS": { "type": "integer", "example": 0 }, "REQUEST_QUEUE_WRITES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_INTERNAL_GBYTES": { "type": "integer", "example": 0 }, "DATA_TRANSFER_EXTERNAL_GBYTES": { "type": "integer", "example": 0 }, "PROXY_RESIDENTIAL_TRANSFER_GBYTES": { "type": "integer", "example": 0 }, "PROXY_SERPS": { "type": "integer", "example": 0 } } } } } } } } } }